Friday, May 09, 2008
Welcome
The overall research theme in our lab is the structural
characterization of complex biological assemblies, their architecture, interactions with different
ligands, and the regulation of their function. Of special interest for us are the structural basis of
microtubule dynamics, and the assembly and regulation of the molecular machineries involved in
transcriptional and translational initiation and on transcription-coupled DNA repair. We are using
electron microscopy, image analysis, and functional biochemical and biophysical assays to gain new
information on these systems and their cellular regulation.