CRISPR
In bacteria and archaea, the clustered regularly interspaced short palindromic repeats (CRISPR)–associated (Cas) targeting complexes use CRISPR RNA (crRNA) guides to bind and destroy complementary nucleic acid targets. In the Type I-E CRISPR-Cas system in E. coli, these CRISPR transcripts are processed into short RNAs that are incorporated into a large ribonucleoprotein surveillance complex called [...]