The Nogales Lab

Wednesday, May 14, 2008


  • One position is available to work on the structural characterization of a number of complex macromolecular assemblies using electron microscopy, image reconstruction and biochemical and biophysical assays. Projects include human transcription initiation complexes, replication, and microtubule cytoskeleton.
  • An additional position is immediately available to work on structural and biochemical characterization of complexes of RNA polymerase II with DNA repair proteins in collaboration with the PK Cooper Lab at LBNL. It is especially urgent to fill this position, so those prepared to move within 6 months are particularly encouraged to apply.
  • The research in our lab should be attractive to those wanting to extend their biophysical or biochemical expertise into the expanding area of cryo-electron microscopy and single particle reconstruction.
  • Berkeley has state-of-the art electron microscopes within an environment of several electron microscopy groups with a very strong tradition in the field, as well as research groups of international caliber in the biological areas we are studying.

  • Ph.D. in Molecular Biology, Biochemistry, Biophysics or an appropriate related field.
  • Researchers with a strong background in biochemistry are of particular interest to our lab.
  • Previous experience purifying and handling large protein complexes will be an extreme plus!
  • Experience in the fields of eukaryotic transcription or DNA repair would be highly valued.
  • Candidate must be able to think independently and work cooperatively.

Please send an e-mail with a brief description of interests and relevant work experience, a resume and names of at three references to Eva Nogales at enogales@lbl.gov.