HHMI UCB LBL

Animations

This QuickTime movie represents a comparison of Structural Models for the Transcrition Preinitiation Complex (PIC).

The animation is available for download in 1024x388 and 1920x728 resolutions.

Structural Models for the Transcription Preinitiation Complex (PIC)

Cryo-EM reconstruction of purified yeast PIC with available crystal structures docked from Murikami, Kornberg and colleagues.
Murikami et al. Science DOI:10.1126/science 1238724 (2013)

Negative stain reconstruction of step-wise assembled humen PIC with available crystal structures docked from He, Nogales and colleagues
He et al. Nature 495, 481-486 (2013)

Cryo-EM reconstruction of partial human PIC (lacking TFIIH) with available crystal structures docked from He, Nogales and colleagues.
He et al. Nature 495, 481-486 (2013)

Microtubules - Structure, Function and Dynamics

This QuickTime movie, representing the work of Eva Nogales and Hong-Wei Wang, was created by Stylus Visualization Studio.

The movie is currently available as a QuickTime container video encoded in H.264 either with or without narration in AAC sound. The narrated version also contains additional footage in the form of a brief introduction.

no sound

nogales_720x480_nosound.mov
(28.8 MB)
H.264 codec, no sound

narrated

nogales_400x300_narrated.mov
(49.6 MB)
H.264/AAC codec, narrated