Animations
The following animations give structural insights of several macrmolecular complexes
Near-atomic model of microtubule-tau interactions
Structures of human PRC2 with its cofactors AEBP2 and JARID2
Cryo-EM structure of subtrate-bound human telomerase holoenzyme
Structural insight into TPX2-simulated microtubule assembly
This QuickTime movie represents a comparison of Structural Models for the Transcrition Preinitiation Complex (PIC).
The animation is available for download in 1024x388 and 1920x728 resolutions.
Structural Models for the Transcription Preinitiation Complex (PIC)
Cryo-EM reconstruction of purified yeast PIC with available crystal structures docked from Murikami, Kornberg and colleagues.
Murikami et al. Science DOI:10.1126/science 1238724 (2013)
Negative stain reconstruction of step-wise assembled humen PIC with available crystal structures docked from He, Nogales and colleagues
He et al. Nature 495, 481-486 (2013)
Cryo-EM reconstruction of partial human PIC (lacking TFIIH) with available crystal structures docked from He, Nogales and colleagues.
He et al. Nature 495, 481-486 (2013)
Microtubules - Structure, Function and Dynamics
This QuickTime movie, representing the work of Eva Nogales and Hong-Wei Wang, was created by Stylus Visualization Studio.
The movie is currently available as a QuickTime container video encoded in H.264 either with or without narration in AAC sound. The narrated version also contains additional footage in the form of a brief introduction.
nogales_720x480_nosound.mov
(28.8 MB)
H.264 codec, no sound
nogales_400x300_narrated.mov
(49.6 MB)
H.264/AAC codec, narrated
News
Recent publications
Rosalind Frank Lecture by Eva Nogales
Eva Nogales is the 2019 recipient of the Grimwade Medal
Eva Nogales has been elected Fellow of ASCB