Animations
This QuickTime movie represents a comparison of Structural Models for the Transcrition Preinitiation Complex (PIC).
The animation is available for download in 1024x388 and 1920x728 resolutions.
Structural Models for the Transcription Preinitiation Complex (PIC)
Cryo-EM reconstruction of purified yeast PIC with available crystal structures docked from Murikami, Kornberg and colleagues.
Murikami et al. Science DOI:10.1126/science 1238724 (2013)
Negative stain reconstruction of step-wise assembled humen PIC with available crystal structures docked from He, Nogales and colleagues
He et al. Nature 495, 481-486 (2013)
Cryo-EM reconstruction of partial human PIC (lacking TFIIH) with available crystal structures docked from He, Nogales and colleagues.
He et al. Nature 495, 481-486 (2013)
Microtubules - Structure, Function and Dynamics
This QuickTime movie, representing the work of Eva Nogales and Hong-Wei Wang, was created by Stylus Visualization Studio.
The movie is currently available at 400x300 resolution, either with or without narration. The narrated version also contains additional footage in the form of a brief introduction.
nogales_400x300.mov (70 MB)
400 x 300 resolution, no sound
(requires QuickTime)
nogales_400x300_narrated.mov (93 MB)
400 x 300 resolution, narrated
(requires QuickTime)
News
Recent publications
Eva Nogales was announced as the receipient of the 2015 Dorothy Crowfoot Hodgkin Award.
This award is sponsored by Genentech, and granted in recognition of exceptional contributions in protein science which profoundly influence our understanding of biology.
Thesis award
David Taylor and Vignesh Kasinath have repectivley received the Damon Runyon and Helen Hay Whitney Postdoctoral Fellowships.
David Taylor received the Mary Ellen Jones Dissertation Prize, which is awarded annually to recognize the most distinguished dissertation in Molecular Biophysics and Biochemistry at Yale University.